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Cryptosporidiosis worsened by commonly used Probiotic

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As reported in the journal Applied and Environmental Microbiology, the team discovered that compared to control mice, those that were given the probiotic had altered gut micro flora and more parasites in their feces.Professor Giovanni Widmer and colleagues from Tufts University had assumed that a healthy microbiome could prevent or reduce the severity of infection.However, contrary to their expectations, they found that the consumption of a commercially available probiotic actually increased the severity of infection.
Cryptosporidiosis is one of the main causes of diarrhea in developing countries. According to The Lancet, the infection killed around 48,000 individuals in 2016. There are no drugs that can treat the infection and no vaccines that can prevent it.Antibiotics, which often cause an imbalance in the normal gut microbiota, can make people more susceptible to gut infections. On the other hand, a healthy balance of microflora can prevent infection or reduce its severity. Prof. Wi…

Kaposi's Sarcoma- A Detailed Information

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The trillions of the cells in the body grow normally, divide, and then die accordingly. Once adulthood is reached cells divide only to replace worn-out or dying cells or to repair injuries.

What happens to cells in cancer?Cancer starts when cells in a certain organ or part of the start to grow out of control. Cells become cancer cells because of damage to DNA. Different types of cancer can behave very differently – some may remain at one location while others spread rapidly to other major organs via blood stream or via lymphatic channels. (1-4) How does Kaposi's sarcoma develop?Kaposi's sarcoma is a cancer that develops from the cell lining the lymph or blood vessels. The cancer appears as red, purple, or brown raised tumors or spots over the skin. These lesions are usually non-symptomatic but may cause painful swelling in some areas like legs, groin or skin around the eyes. Kaposi's sarcoma may become life threatening when it affects major organ like lungs, liver, or the gastr…

Conditions of first sexual encounter can be indicators of future HIV risk and gender-based violence

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Adolescent girls and young women in Mombasa, Kenya are more likely to experience Higher risks of HIV and gender-based violence when they are involved with sex work venues or have sexual experiences at a young age, suggests a study co-led by St. Michael's Hospital and the University of Manitoba in Canada.
Published in the Journal of Acquired Immune Deficiency Syndromes (JAIDS), the research suggests that the conditions of a first sexual encounter, such as a woman's age, the man's age, use of condoms, and whether or not the encounter is consensual can be indicators of future risk of HIV infection and gender-based violence.The research team found that adolescent girls and young women in Mombasa, Kenya, who are forced or coerced in their first sexual experience, are four to five times more likely to face ongoing gender-based violence throughout their lifetime. This research also showed that one in four participants experience gender-based violence after their first sexual exper…

Scientists took another step towards creating an HIV vaccine

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The scientific group of Peter the Great St.Petersburg Polytechnic University headed by Professor Andrei Kozlov published the results of a study devoted to the search of solutions for creating the HIV vaccine
During two years, with the support of the Russian Science Foundation's grant, researchers studied features of transmitted variants of HIV-1 virus. This type of HIV transmission is most typical for Russian Federation. Within the framework of the project, scientists have studied blood samples of injecting drug users with acute or early stages of HIV infection. The transmission of only one viral variant was detected in 70% of cases. These data were obtained by the method of single genome analysis (SGA), which allows to analyze 20-30 single genomes. In addition, the scientific group used the next-generation sequencing approach (NGS), capable of analyzing up to 5000 genomes. Thus, scientists managed to establish that all viruses are the "descendants" of any one virus part…

Science Validates Undetectable = Untransmittable HIV Prevention Message

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People living with HIV whose virus is completely, durably suppressed by treatment will not sexually transmit the virus to an HIV-negative partner, according to NIAID Director Anthony S Fauci, M.D. The success of this HIV prevention strategy is contingent on achieving and maintaining an undetectable viral load—the amount of HIV genetic material in the blood—by taking medication to treat HIV daily as directed.
Dr. Fauci delivered these remarks at the July 22 U=U 2018: Celebrate, Activate and Implement! meeting held prior to the 22nd International AIDS Conference (AIDS 2018) in Amsterdam. Over the past two years, a grassroots movement has emerged to promote the value of HIV treatment as prevention through the “Undetectable = Untransmittable” campaign, also known as U=U. In his keynote lecture titled “U=U: Science and Policy,” Dr. Fauci traced the science behind the U=U message from early observational studies to more recent, large clinical trials. For nearly two decades, scientists have rec…

Trial of ‘kick and kill’ approach to HIV cure leaves puzzles to be solved

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Researchers have reported the results of the first randomized clinical trial to test a novel strategy.
The approach involves waking up and then killing the ‘sleeping’ HIV that is hiding in the body using an experimental approach known as ‘kick and kill’. Led by Imperial College London, the University of OxfordMRC Clinical Trials Unit at UCL, and the University of Cambridge, the RIVER study aimed to improve on current care by eradicating HIV from the body, which would represent a major step forward in the search for a cure. The RIVER study, which ran from 2015 to 2018 in London and Brighton, tested the ‘kick and kill’ approach in 60 men recently diagnosed with HIV and who had the virus under control by taking ART.Although investigators found no difference in effect between those participants who received the active ‘kick and kill’ therapy and those who had standard treatment, they say the trial paves the way for testing different combinations of therapies to tackle the HIV that persists…

Combe announces launch of Preventeza Emergency Contraceptive and campaign

As current technologies are advancing more in finding out solutions for health problems, they are marching forward with little steps starting from prevention to cure.One such kind of prevention for unplanned pregnancies and to avoid certain complicated pregnancies Vagisil have announced  a newer method for prevention weeks before.  Combe Inc., the makers of Vagisil®,announced the launch of its Preventeza Emergency Contraceptive (levonorgestrel tablet, 1.5 mg)  to showcase solidarity around women's reproductive rights. To demonstrate its commitment to helping women learn more about emergency contraception (EC), the Company is planning to give away up to $1 million worth of free product via the launch of its "Buy One Get One or Give One (BoGoGo)" product campaign where women who purchase Preventeza on Vagisil.com will have the option to get a second one for free to either keep on hand or to give to another woman in their life. New Preventeza by Vagisil, available online or o…